器官芯片
GB 循环灌流芯片
货号： GBOC0003
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产品规格
| 货号 | GBOC0003 |
|---|---|
| 产品名称 | GB 循环灌流芯片 |
| 产品分类 | 器官芯片 |
| 规格 / 包装 | 4 chips/box, sterile. |
| 储存条件 | Store at room temperature (15-25 C). Protect from dust and physical damage. |
| 有效期 | 12 months |
产品描述
以下为英文原文说明，中文产品资料与实验方案请联系技术支持索取。
The Circular Perfusion Chip consists of a central loading well and surrounding branching culture units. It can be paired with an upstream concentration gradient generator to produce different drug concentration gradients for multi-concentration drug screening. Each branching culture unit can capture and culture organoids or cell spheroids, and perfusion and vascularization are achieved through microchannels connected to the outer ring, enabling timely signal molecule transfer through adequate exchange of oxygen and nutrients.
产品特点
- High-throughput, uniform, dynamic culture: The chip rapidly adjusts nutrition, drug concentration, and hydrodynamic environment to control cell generation processes, enabling high-throughput generation and culture of cells or organoids across multiple culture units.
- Vascularization and nutrient exchange: The circular perfusion units promote vascularization and enable adequate oxygen and nutrient exchange through microchannels, helping simulate in vivo intercellular signal transduction and providing physiological microenvironment conditions closer to the native state.
- Continuous perfusion generates stable fluid shear force to simulate the in vivo circulatory microenvironment.
- High-throughput drug screening and precise evaluation: Through concentration gradient variations, the chip enables multi-concentration, multi-drug combination screening within a single experiment, greatly improving screening throughput and efficiency.
- Scalable and flexible configuration: The chip design supports simultaneous experimentation with multiple circular perfusion units, accommodating different scales and experimental configurations.
- Dynamic perfusion culture accelerates organoid growth (3-5x faster than static culture), shortening in vitro culture cycles to meet clinical sample drug sensitivity testing timelines.
- Can be integrated with upstream drug concentration gradient generators and supports multiple sample types.
应用领域
- Drug screening, dose optimization, and combination therapy research.
- Cell-drug interaction mechanism studies.
- Tumor microenvironment simulation.
- Development of clinical personalized treatment protocols.
注意事项
- 仅供科研使用，不可用于诊断或治疗。
- 所有产品均经过无菌与性能验证等严格质量检测。
- 如需实验方案优化与问题排查协助，请联系我们的技术支持团队。
- 更多验证数据正在整理，将陆续上传。