猴源类器官完全培养基
猴结肠类器官完全培养基
货号： GBCM0071
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产品规格
| 产品名称 | 猴结肠类器官完全培养基 |
|---|---|
| 规格 | 100mL |
| 质控标准 | pH: 7.2~7.4Endotoxin content: <10 EU/mLBiosafety: Negative for bacteria, fungi, and mycoplasma detectionPerformance test: Passed organoid culture test |
| 储存条件 | Store at -20℃,valid for 6 months.Store at 2-8℃valid for 2 weeks.Once thawed, use immediately. Do not refreeze. Can be aliquoted and stored according to your needs. |
| 注意事项 | Upon receipt, store immediately in a -20°C freezer, or aliquot and store in a 2-8°C refrigerator.When unpacking, check for any leakage or damage.Use aseptic techniques during product handling to avoid contamination. |
产品描述
以下为英文原文说明，中文产品资料与实验方案请联系技术支持索取。
细胞来源与组织特征：
The colon organoids of the crab-eating monkey (Macaca fascicularis, also known as cynomolgus monkey or crab-eating monkey) are derived from the stem cells of the colon of adult crab-eating monkeys.The colon tissue is located at the end of the digestive tract. Its main functions are water absorption and electrolyte balance. Its epithelium is composed of absorbent cells (enterocytes), goblet cells (goblet cells), enteroendocrine cells (EECs) and stem cells.Crab-eating monkeys are highly evolutionarily close to humans (genomic similarity is about 93%) and are an important model animal for pharmacokinetics and toxicology research.The colonoid organoids retain the ability of intestinal stem cells to self-renew and differentiate in multiple directions, and can reproduce the crypt-villi-like structure of the colon epithelium in the body.In 2021, Li et al. established the colon organoid of crab-eating monkeys for the first time and confirmed its application value in drug toxicity testing.The colon organoids of crab-eating monkeys can be cultured for a long time for at least 15 generations (about 75 days). The expression of stem cells and TA cell markers is higher than that of primary tissues, but the expression of enteroendocrine cell markers Chga and Chgb is lower in organoids.
The colon organoids of the crab-eating monkey (Macaca fascicularis, also known as cynomolgus monkey or crab-eating monkey) are derived from the stem cells of the colon of adult crab-eating monkeys.The colon tissue is located at the end of the digestive tract. Its main functions are water absorption and electrolyte balance. Its epithelium is composed of absorbent cells (enterocytes), goblet cells (goblet cells), enteroendocrine cells (EECs) and stem cells.Crab-eating monkeys are highly evolutionarily close to humans (genomic similarity is about 93%) and are an important model animal for pharmacokinetics and toxicology research.The colonoid organoids retain the ability of intestinal stem cells to self-renew and differentiate in multiple directions, and can reproduce the crypt-villi-like structure of the colon epithelium in the body.In 2021, Li et al. established the colon organoid of crab-eating monkeys for the first time and confirmed its application value in drug toxicity testing.The colon organoids of crab-eating monkeys can be cultured for a long time for at least 15 generations (about 75 days). The expression of stem cells and TA cell markers is higher than that of primary tissues, but the expression of enteroendocrine cell markers Chga and Chgb is lower in organoids.
猴结肠类器官完全培养基 is a high-performance complete medium specifically designed for Monkey Colonic Organoid culture. This advanced formulation employs optimized nutrient composition and growth factor cocktails to precisely mimic the in vivo tissue microenvironment, supporting long-term establishment, expansion, and maintenance of organoids from primary tissue samples.
猴结肠类器官完全培养基 is suitable for multiple applications including precision medicine research, high-throughput drug screening, toxicity testing, developmental biology studies, and organoid biobanking. The product undergoes rigorous quality control including sterility testing, endotoxin detection, functional validation using established organoid lines, and batch-to-batch consistency checks.
猴结肠类器官完全培养基 is suitable for multiple applications including precision medicine research, high-throughput drug screening, toxicity testing, developmental biology studies, and organoid biobanking. The product undergoes rigorous quality control including sterility testing, endotoxin detection, functional validation using established organoid lines, and batch-to-batch consistency checks.
注意事项
- 仅供科研使用，不可用于诊断或治疗。
- 所有产品均经过无菌与性能验证等严格质量检测。
- 如需实验方案优化与问题排查协助，请联系我们的技术支持团队。
- 更多验证数据正在整理，将陆续上传。