人源类器官完全培养基
人慢阻肺肺类器官完全培养基
货号： GBCM0008
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产品规格
| 产品名称 | 人慢阻肺肺类器官完全培养基 |
|---|---|
| 规格 | 100mL |
| 质控标准 | pH: 7.2~7.4Endotoxin content: <10 EU/mLBiosafety: Negative for bacteria, fungi, and mycoplasma detectionPerformance test: Passed organoid culture test |
| 储存条件 | Store at -20℃,valid for 6 months.Store at 2-8℃valid for 2 weeks.Once thawed, use immediately. Do not refreeze. Can be aliquoted and stored according to your needs. |
| 注意事项 | Upon receipt, store immediately in a -20°C freezer, or aliquot and store in a 2-8°C refrigerator.When unpacking, check for any leakage or damage.Use aseptic techniques during product handling to avoid contamination. |
产品描述
以下为英文原文说明，中文产品资料与实验方案请联系技术支持索取。
细胞来源与组织特征：
Chronic obstructive pulmonary disease (COPD) is a chronic inflammatory disease characterized by persistent respiratory symptoms and irreversible airflow restriction, mainly caused by smoking and exposure to air pollutants.COPD pulmonary organoids are derived from airway biopsy (bronchi) or nasal mucosa tissue of COPD patients, and can also be established by exposing normal organoids to cigarette smoke extract (CSE).COPD organoids retain the characteristic pathological changes of the disease: goblet cell hyperplasia, increased MUC5AC expression, decreased cilia and decreased frequency of cilia pulsation.Chan et al. (2022) systematically established COPD nasal mucosa and bronchial organoids for the first time, and found that they showed disease characteristics consistent with the body, including secretory cell metaplasia and abnormal differentiation trajectories of airway epithelium.COPD organoids can be used to study host-pathogen interactions (such as SARS-CoV-2 and Pseudomonas aeruginosa infections), and it has been found that COPD organoids produce a stronger pro-inflammatory response to viral and bacterial exposure.
Chronic obstructive pulmonary disease (COPD) is a chronic inflammatory disease characterized by persistent respiratory symptoms and irreversible airflow restriction, mainly caused by smoking and exposure to air pollutants.COPD pulmonary organoids are derived from airway biopsy (bronchi) or nasal mucosa tissue of COPD patients, and can also be established by exposing normal organoids to cigarette smoke extract (CSE).COPD organoids retain the characteristic pathological changes of the disease: goblet cell hyperplasia, increased MUC5AC expression, decreased cilia and decreased frequency of cilia pulsation.Chan et al. (2022) systematically established COPD nasal mucosa and bronchial organoids for the first time, and found that they showed disease characteristics consistent with the body, including secretory cell metaplasia and abnormal differentiation trajectories of airway epithelium.COPD organoids can be used to study host-pathogen interactions (such as SARS-CoV-2 and Pseudomonas aeruginosa infections), and it has been found that COPD organoids produce a stronger pro-inflammatory response to viral and bacterial exposure.
人慢阻肺肺类器官完全培养基 is a high-performance complete medium specifically designed for Human COPD Lung Organoid culture. This advanced formulation employs optimized nutrient composition and growth factor cocktails to precisely mimic the in vivo tissue microenvironment, supporting long-term establishment, expansion, and maintenance of organoids from primary tissue samples.
人慢阻肺肺类器官完全培养基 is suitable for multiple applications including precision medicine research, high-throughput drug screening, toxicity testing, developmental biology studies, and organoid biobanking. The product undergoes rigorous quality control including sterility testing, endotoxin detection, functional validation using established organoid lines, and batch-to-batch consistency checks.
人慢阻肺肺类器官完全培养基 is suitable for multiple applications including precision medicine research, high-throughput drug screening, toxicity testing, developmental biology studies, and organoid biobanking. The product undergoes rigorous quality control including sterility testing, endotoxin detection, functional validation using established organoid lines, and batch-to-batch consistency checks.
注意事项
- 仅供科研使用，不可用于诊断或治疗。
- 所有产品均经过无菌与性能验证等严格质量检测。
- 如需实验方案优化与问题排查协助，请联系我们的技术支持团队。
- 更多验证数据正在整理，将陆续上传。