人源类器官完全培养基
人结直肠癌类器官完全培养基
货号： GBCM0007
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产品规格
| 产品名称 | 人结直肠癌类器官完全培养基 |
|---|---|
| 规格 | 100mL |
| 质控标准 | pH: 7.2~7.4Endotoxin content: <10 EU/mLBiosafety: Negative for bacteria, fungi, and mycoplasma detectionPerformance test: Passed organoid culture test |
| 储存条件 | Store at -20℃,valid for 6 months.Store at 2-8℃valid for 2 weeks.Once thawed, use immediately. Do not refreeze. Can be aliquoted and stored according to your needs. |
| 注意事项 | Upon receipt, store immediately in a -20°C freezer, or aliquot and store in a 2-8°C refrigerator.When unpacking, check for any leakage or damage.Use aseptic techniques during product handling to avoid contamination. |
产品描述
以下为英文原文说明，中文产品资料与实验方案请联系技术支持索取。
细胞来源与组织特征：
Colorectal cancer (CRC) is the third most common malignant tumor in the world.The development of CRC follows the "adenoma-adenocarcinoma sequence", which involves progressive mutations in key driver genes such as APC, KRAS, SMAD4, and TP53.According to molecular characteristics, it can be divided into four consensus molecular subtypes: CMS1 (microsatellite unstable/immune type), CMS2 (typical/WNT-driven type), CMS3 (metabolic type) and CMS4 (interstitial type).Patient-derived CRC organoids can accurately reproduce the histopathological characteristics, gene mutation profiles and drug response of the primary tumor, and are one of the most important preclinical models in CRC research.Compared with normal intestinal organoids, CRC organoids usually exhibit constitutive activation of the Wnt pathway (such as APC mutations or β-catenin activation mutations), so they can grow without exogenous Wnt3a and R-spondin.
Colorectal cancer (CRC) is the third most common malignant tumor in the world.The development of CRC follows the "adenoma-adenocarcinoma sequence", which involves progressive mutations in key driver genes such as APC, KRAS, SMAD4, and TP53.According to molecular characteristics, it can be divided into four consensus molecular subtypes: CMS1 (microsatellite unstable/immune type), CMS2 (typical/WNT-driven type), CMS3 (metabolic type) and CMS4 (interstitial type).Patient-derived CRC organoids can accurately reproduce the histopathological characteristics, gene mutation profiles and drug response of the primary tumor, and are one of the most important preclinical models in CRC research.Compared with normal intestinal organoids, CRC organoids usually exhibit constitutive activation of the Wnt pathway (such as APC mutations or β-catenin activation mutations), so they can grow without exogenous Wnt3a and R-spondin.
人结直肠癌类器官完全培养基 is a high-performance complete medium specifically designed for Human Colorectal Cancer Organoid culture. This advanced formulation employs optimized nutrient composition and growth factor cocktails to precisely mimic the in vivo tissue microenvironment, supporting long-term establishment, expansion, and maintenance of organoids from primary tissue samples.
人结直肠癌类器官完全培养基 is suitable for multiple applications including precision medicine research, high-throughput drug screening, toxicity testing, developmental biology studies, and organoid biobanking. The product undergoes rigorous quality control including sterility testing, endotoxin detection, functional validation using established organoid lines, and batch-to-batch consistency checks.
人结直肠癌类器官完全培养基 is suitable for multiple applications including precision medicine research, high-throughput drug screening, toxicity testing, developmental biology studies, and organoid biobanking. The product undergoes rigorous quality control including sterility testing, endotoxin detection, functional validation using established organoid lines, and batch-to-batch consistency checks.
注意事项
- 仅供科研使用，不可用于诊断或治疗。
- 所有产品均经过无菌与性能验证等严格质量检测。
- 如需实验方案优化与问题排查协助，请联系我们的技术支持团队。
- 更多验证数据正在整理，将陆续上传。